University of Montpellier scientists provide us how depressive disorder is related to cholesterol and gender

August 26, 2010

Written by: Betty Doyle

Do you know the Institute of Medical and Health Research (INSERM) and School of Montpellier funded experts pointed that controlling ‘good’ and ‘bad’ levels of cholesterol can help avoid mental problems among seniors?

In a freshly released issue of the academic journal Biological Psychiatry ( released in July 2010, leading researcher Dr. Marie-Laure Ancelin of INSERM (Institut National de la Santé et de la Recherche Médicale documented that gender-specific regulation of cholesterol levels can help reduce depression in the seniors.

French scientists followed a considerable group of men and women aged sixty five and older for 7 years.

They observed that depressive disorder in women was linked with low levels of “good” high-density lipoprotein cholesterol (HDL-C), which puts them at higher risk for coronary disease, including heart stroke.

In contrast, depression in men was related to low levels of “bad” low-density lipoprotein cholesterol (LDL-C). This association was strongest in men with a genetic vulnerability to depression related to a serotonin transporter gene.

Therefore, proper regulation of HDL-C and LDL-C levels can aid avoid depressive disorder in the aging seniors, the study concluded.

The analysis appeared in the July 15 issue of the journal Biological Psychiatry (Reference:

Major nutritional sources of cholesterol include dairy products, egg yolks, beef, pork, poultry, and shrimp. Plant products such as flax seeds and peanuts have cholesterol-like substances called phytosterols.

Total cholesterol is described as the sum of HDL (High-density lipoprotein), LDL (Low-density lipoprotein), and VLDL (Very-low-density lipoprotein). Usually, only the total, HDL, and triglycerides are tested.

It is recommended to have cholesterol tested more often than 5 years if a person has total cholesterol of 200 mg/dL or more, or if a man over age forty five or a woman over age 50 has HDL (good) cholesterol under 40 mg/dL, or exist other risk elements for coronary disease and stroke.

So…what can you do to rise your HDL (good) and reduce your LDL (bad) levels?
1. Physical exercise can substantially improve HDL cholesterol while lowering LDL cholesterol.
2. Smoking cigarettes has been shown to lower HDL while raising LDL cholesterol.
3. Processed, trans fats at the same time raise LDL cholesterol and lower HDL cholesterol.
4. Monounsaturated fats such as those found in extra virgin olive oil and avocados increase HDL and lower LDL.
5. Fatty fish like salmon and sardines contain omega-3 fats that raise HDL and lower LDL.
6. Whole, intact cereals contain soluble fiber and niacin, both of which raise HDL and may lower LDL.

Now it’s all to you…

About the author – Betty Doyle publishes articles for the depression pills blog. It’s a nonprofit website dedicated to her personal depression journey. The blog is focused on giving energy and hope to any individual who is suffering from depressive disorder and supports those people to find the energy to fight against the effects of depression. With this she would like to aid alleviate some of the stigma mental illness depression can cause and help the public perception of mood diseases.


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